Nanotechnology is a field of science which deals with materials in nano
scale. Nano-materials display unique mechanical, electrical, chemical, and
optical properties. By understanding the properties of nano materials; we can use
in research, diagnosis and therapy of heart, lung, blood and sleep. Nanotechnology
will offer novel techniques in the treatment of a multitude of diseases,
including cardiovascular disorders. Ischemic heart conditions are some of the most
prevalent disorders in many parts of the world. In each year death rate is
increased significantly due to heart disease. Even-though ischemic and infarct
heart disease are treated in advanced methods, it mainly leads to heart
failure.
Death mainly occurs due
to the inability to provide medication to the affected area, lack of stem cell
implantation, tissue regeneration, and additional damage in ischemic tissue.
The promising results have been shown in therapeutic environment by application
of nanotechnology. Several nanotechnology based treatments for ischemic heart
diseases including simple and modified drug/stem cell delivery systems ranging
from magnetic, antibody-linked, and mesoporous silica nano-particles.
Nano-particles vehicles
have emerged on an approach for the site-selective delivery of therapeutic
agents to areas of the injured or dysfunctional vascular wall including
vascular segments at risk for restenosis following per-cutaneous coronary
interventions. This approach infusion allows for a targeted delivery of
compounds to sites of vascular dysfunction or injury. Components of the technology
include a combination of known / approved ultrasound contrast vascular imaging agents
complexed with therapeutic agents. A number of therapeutic agents have been
explored for incorporation into the nano-particle delivery vehicle and for
efficacy on re-stenosis
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